Genetic Predispositions: What are the odds?
If you have a genetic mutation sometimes called a genetic predisposition will you necessarily develop cancer?
The simple answer is remarkably no. For examples in those people with the BRAC I (Breast and ovarian cancer) mutation only 65-70% will develop cancer by the age of 80, BRCA II (Breast and ovarian cancer )45-55%, JAK2 (Polycythemia Vera and other myeloprolifeative disorders) 2% and MSH2 (Lynch Syndrome and colorectal cancers)70% by the age of 60.
So why do some people with these common mutations never develop cancer?
According to an article published in the Proceedings of the National Academy of Sciences, entitled 'Toward a genetics of cancer resistance' four factors make up cancer resisters naturally in the body. These include:
- Immunological (innate immunity)
- DNA repair processes
-Epigenetics (gene expression and external effectors)
-Apoptosis (intrecellular mechanisms)
These resistance factors are part of a normally working cell cycle, however they can be assisted by Restorative Health elements:
-Social and Emotional Wellness
-Herbs and Supplements
- Sense of Purpose
(For more information on Restorative Health please check out the Webinar on my web site)
All these elements have been studied and shown to impact innate immunity, and inflammation which directly or indirectly affects the capacity of the cell cycle to function properly even with mutations.
Make sure your clinician addresses the Restorative Health factors in your treatment plan.