Genetic Predispositions: What are the odds?
If you have a genetic mutation sometimes called a genetic predisposition will you necessarily develop cancer? The simple answer is remarkably no. For examples in those people with the BRAC I (Breast and ovarian cancer) mutation only 65-70% will develop cancer by the age of 80, BRCA II (Breast and ovarian cancer )45-55%, JAK2 (Polycythemia Vera and other myeloprolifeative disorders) 2% and MSH2 (Lynch Syndrome and colorectal cancers)70% by the age of 60. So why do some people